Recombinant Human C-C motif chemokine 3-like 1 protein (CCL3L1)

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產品詳情

純度：

>97% as determined by SDS-PAGE.
內毒素：

Less than 1.0 EU/μg as determined by LAL method.
生物活性：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
基因名：

CCL3L1
Uniprot No.：

P16619
別名：

464.2; C-C motif chemokine 3-like 1; CCL3L3; CL3L1_HUMAN; D17S1718; G0/G1 switch regulatory protein 19-2; G0S19-2; LD78; LD78-beta(1-70); LD78-beta(5-70); LD78BETA; PAT 464.2; SCYA3L; SCYA3L1; Small-inducible cytokine A3-like 1; Tonsillar lymphocyte LD78 beta protein
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
來源：

E.Coli
分子量：

7.8 kDa
表達區(qū)域：

24-93aa
氨基酸序列

APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
蛋白標簽：

Tag-Free
產品提供形式：

Liquid or Lyophilized powder
緩沖液：

0.2 μm filtered PBS, pH 7.4 ,lyophilized
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

5-10 business days
Datasheet & COA：

Please contact us to get it.

功能：

Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
基因功能參考文獻：
1. severe periodontal tissue destruction in Papillon-Lefevre syndrome may be related to excess accumulation of LD78beta and LD78alpha and dysregulation of the microbial-induced inflammatory response in the periodontium PMID: 15728180
亞細胞定位：

Secreted.
蛋白家族：

Intercrine beta (chemokine CC) family
數(shù)據(jù)庫鏈接：

HGNC: 10628

OMIM: 601395

KEGG: hsa:414062

STRING: 9606.ENSP00000408984

UniGene: Hs.454713