CCL11
CCL11，即C-C motif chemokine ligand 11，也被稱作Eotaxin-1，是一種小型誘導性細胞因子，屬于C-C基序趨化因子家族成員之一。它在多種免疫細胞的遷移和活化中發(fā)揮關鍵作用，尤其是對嗜酸性粒細胞、嗜堿性粒細胞和Th2淋巴細胞具有強烈的化學吸引作用。CCL11通過與趨化因子受體如CCR2、CCR3和CCR5結合來發(fā)揮作用，其中CCR3是介導CCL11生物學效應的主要受體。CCL11參與了多種生理和病理過程，包括哮喘時嗜酸性粒細胞的歸巢、腫瘤微環(huán)境中免疫細胞的招募以及在衰老和神經退行性疾病中的潛在作用。研究表明，CCL11在老年人中表達上調，并與某些年齡相關疾病的發(fā)展相關聯。此外，CCL11的表達還與腫瘤微環(huán)境的免疫調節(jié)有關，可能影響腫瘤的發(fā)展和患者的預后。
熱銷產品
CCL11 Antibody (CSB-PA004775ESR2HU)
驗證數據
Western blot
All lanes: CCL11 antibody at 5μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004775ESR2HU at dilution of 1:100
Rat Eotaxin 1 (Eotaxin 1/CCL11/ECF)ELISA Kit (CSB-E07319r)
驗證數據
貨號：CSB-E07319r
規(guī)格：96T/48T
靈敏度：3.9 pg/ml
檢測范圍：15.6 pg/ml -1000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CCL11 Antibodies
CCL11 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004775GA01HU | CCL11 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004775ESR2HU | CCL11 Antibody | Human | ELISA, WB, IHC |
| CSB-PA005780 | CCL11 Antibody | Human,Mouse,Rat | WB, ELISA |
CCL11 Proteins
CCL11 Proteins for Cavia porcellus (Guinea pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004775GU CSB-EP004775GU CSB-BP004775GU CSB-MP004775GU CSB-EP004775GU-B |
Recombinant Guinea pig Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004775RA CSB-EP004775RA CSB-BP004775RA CSB-MP004775RA CSB-EP004775RA-B |
Recombinant Rat Eotaxin (Ccl11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001561RA | Recombinant Rat Eotaxin protein (Ccl11) | E.Coli |
CCL11 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004775MO CSB-EP004775MO CSB-BP004775MO CSB-MP004775MO CSB-EP004775MO-B |
Recombinant Mouse Eotaxin (Ccl11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001291MO | Recombinant Mouse Eotaxin protein (Ccl11) | E.Coli |
CCL11 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004775HU CSB-BP004775HU CSB-MP004775HU CSB-EP004775HU-B |
Recombinant Human Eotaxin (CCL11) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000901HU | Recombinant Human Eotaxin protein (CCL11) | E.Coli |
| CSB-EP004775HU | Recombinant Human Eotaxin (CCL11) | E.coli |
CCL11 Proteins for Macaca mulatta (Rhesus macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850742MOW CSB-EP850742MOW CSB-BP850742MOW CSB-MP850742MOW CSB-EP850742MOW-B |
Recombinant Macaca mulatta Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001041MOW | Recombinant Rhesus Macaque Eotaxin protein (CCL11) | E.Coli |
CCL11 Proteins for Equus caballus (Horse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP890591HO CSB-EP890591HO CSB-BP890591HO CSB-MP890591HO CSB-EP890591HO-B |
Recombinant Horse Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP890592BO CSB-EP890592BO CSB-BP890592BO CSB-MP890592BO CSB-EP890592BO-B |
Recombinant Bovine Eotaxin (CCL11) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL11 ELISA Kit
CCL11 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04533h | Human eosinophil chemotactic factor,ECF ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 7.8 pg/mL |
CCL11 ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07319r | Rat Eotaxin 1 (Eotaxin 1/CCL11/ECF)ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
