BAG4 Antibody
-
中文名稱：BAG4兔多克隆抗體
-
貨號：CSB-PA002532GA01HU
-
規格：￥3,900
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：BAG 4 antibody; BAG family molecular chaperone regulator 4 antibody; BAG-4 antibody; BAG4 antibody; BAG4_HUMAN antibody; Bcl 2 associated athanogene 4 antibody; Bcl-2-associated athanogene 4 antibody; BCL2 associated athanogene 4 antibody; Silencer of death domains antibody; SODD antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Human BAG4
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產品提供形式：Liquid
-
應用范圍：ELISA,WB
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria.
-
基因功能參考文獻：
- AGS cells overexpressing BAG4 exhibited a significant increase in the percentage of cells in the G1/G0 peak and transfection of shRNA decrese demonstrated the opposite effect. PMID: 29067445
- acid-induced increase in SODD expression and decrease in cell apoptosis may depend on the activation of NOX5-S and NF-kappaB1 p50 in FLO cells PMID: 27756772
- SGK1.1 regulates gene transcription upon a different set of genes some of which participate in cell survival pathways (BAG-4) and others in intracellular vesicular traffic (Brox). PMID: 25849655
- SODD over-expression might be correlated with the clinical classification, curative effect, and prognosis of ALL cells. PMID: 24737427
- MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD). PMID: 23190898
- Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells. PMID: 12017295
- SODD/BAG-4 is not only a silencer of TNFR1 but also a modulator of CD95 activity, regulating the balance of both death-promoting and -depressing signals PMID: 12706861
- BAG-4 functions as a negative regulator for apobec-1-mediated apoB mRNA editing PMID: 14559896
- Gene induces transformed phenotype when overexpressed in a cancer breast cell line. PMID: 17178857
- results of analysis of the genome-wide scan data was a 20 cM region at 8p11-23 in which markers had LODs > or =1.0. Linkage and association analyses of these SNPs yield suggestive results for markers in FGFR1 and BAG4. PMID: 17366557
- Vincristine induces Jurkat cell apoptosis by downregulating expression of SODD protein and priming the death receptor pathway. PMID: 17605853
顯示更多
收起更多
-
亞細胞定位：Cytoplasm.
-
組織特異性：Ubiquitous.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
