NT5E
NT5E，即5'-核苷酸外酶，別名CD73、eN、eNT、CALJA。NT5E蛋白是一種細胞表面酶，主要功能是催化細胞外的核苷酸轉(zhuǎn)化為可透過膜的核苷，這一過程對于調(diào)節(jié)細胞外的ATP水平和腺苷信號至關重要。NT5E通過將ATP轉(zhuǎn)化為腺苷，進而影響免疫細胞的功能和炎癥反應。
在生物學意義上，NT5E在多種生理和病理過程中發(fā)揮作用，包括淋巴細胞分化、免疫調(diào)節(jié)以及腫瘤微環(huán)境中的免疫逃逸。NT5E的異常表達與多種疾病相關，如關節(jié)和動脈的鈣化、炎癥性腸病以及某些癌癥。
熱銷產(chǎn)品
Recombinant Human 5'-nucleotidase (NT5E) (Active) (CSB-MP723415HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized CD73 at 2 μg/ml can bind Anti- CD73 Rabbit Monoclonal Antibody(CSB-RA978310A0HU), the EC50 is 3.212-4.525 ng/ml.
NT5E Recombinant Monoclonal Antibody (CSB-RA723415MA1HU)
驗證數(shù)據(jù)
Overlay Peak curve showing PC3 cells surface stained with CSB-RA723415MA1HU (red line) at 1:100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was mouse IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
NT5E Antibodies
NT5E for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA420339 | NT5E Antibody | Human | WB, ELISA |
| CSB-PA564996 | NT5E Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA823804 | NT5E Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA10529A0Rb | NT5E Antibody | Human | ELISA, WB, IHC |
| CSB-PA10529B0Rb | NT5E Antibody, HRP conjugated | Human | ELISA |
| CSB-PA10529C0Rb | NT5E Antibody, FITC conjugated | Human | |
| CSB-PA10529D0Rb | NT5E Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA978310A0HU | NT5E Recombinant Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA723415MA1HU | NT5E Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
NT5E Proteins
NT5E Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723415MO CSB-EP723415MO CSB-BP723415MO CSB-MP723415MO CSB-EP723415MO-B |
Recombinant Mouse 5'-nucleotidase (Nt5e) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP005101MO | Recombinant Mouse 5'-nucleotidase (Nt5e), partial (Active) | Mammalian cell |
NT5E Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP723415HU1 | Recombinant Human 5\'-nucleotidase (NT5E), partial | E.coli |
| CSB-EP723415HU1b1 | Recombinant Human 5'-nucleotidase (NT5E), partial | E.coli |
| CSB-AP005071HU | Recombinant Human 5'-nucleotidase (NT5E), partial (Active) | Mammalian cell |
| CSB-MP723415HU | Recombinant Human 5'-nucleotidase (NT5E) (Active) | Mammalian cell |
NT5E ELISA Kit
NT5E ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04682m | Mouse 5-Nucleotidase,5-NT ELISA Kit | serum, plasma, tissue homogenates | 0.031 mU/mL |
NT5E ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14099h | Human cluster of differentiation 73(CD73) ELISA Kit | serum, plasma, tissue homogenates | 0.78 ng/mL |
NT5E ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14100r | Rat 5'-nucleotidase/cluster of differentiation 73 (NT5E/CD73) ELISA kit | serum, plasma, tissue homogenates, cell culture supernates | 0.156 mIU/mL |
