Recombinant Human Leucine-rich repeat-containing protein 25 (LRRC25), partial

中文名稱(chēng)：

人LRRC25重組蛋白
貨號(hào)：

CSB-YP854030HU
說(shuō)明書(shū)：

Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

人LRRC25重組蛋白
貨號(hào)：

CSB-EP854030HU
說(shuō)明書(shū)：

Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

人LRRC25重組蛋白
貨號(hào)：

CSB-EP854030HU-B
說(shuō)明書(shū)：

Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

人LRRC25重組蛋白
貨號(hào)：

CSB-BP854030HU
說(shuō)明書(shū)：

Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

人LRRC25重組蛋白
貨號(hào)：

CSB-MP854030HU
說(shuō)明書(shū)：

Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

LRRC25
Uniprot No.：

Q8N386
別名：

LRRC25; MAPA; UNQ6169/PRO20174Leucine-rich repeat-containing protein 25; Monocyte and plasmacytoid-activated protein
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy. Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.
基因功能參考文獻(xiàn)：
1. The findings identify a previously unrecognized role of LRRC25 in type I interferon signaling activation by which LRRC25 acts as a secondary receptor to assist RIG-I delivery to autophagosomes for degradation in a p62-dependent manner. PMID: 29288164
亞細(xì)胞定位：

Membrane; Single-pass type I membrane protein. Cytoplasm.
組織特異性：

Expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in
數(shù)據(jù)庫(kù)鏈接：

HGNC: 29806

OMIM: 607518

KEGG: hsa:126364

STRING: 9606.ENSP00000340983

UniGene: Hs.332156