Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), partial

中文名稱：

人MAP4K5重組蛋白
貨號(hào)：

CSB-YP013440HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人MAP4K5重組蛋白
貨號(hào)：

CSB-EP013440HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人MAP4K5重組蛋白
貨號(hào)：

CSB-EP013440HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MAP4K5重組蛋白
貨號(hào)：

CSB-BP013440HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人MAP4K5重組蛋白
貨號(hào)：

CSB-MP013440HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

MAP4K5
Uniprot No.：

Q9Y4K4
別名：

MAP4K5; Mitogen-activated protein kinase kinase kinase kinase 5; EC 2.7.11.1; Kinase homologous to SPS1/STE20; KHS; MAPK/ERK kinase kinase kinase 5; MEK kinase kinase 5; MEKKK 5
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
基因功能參考文獻(xiàn)：
1. MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma. PMID: 27023625
2. TNF signaling leads to oligomerization, ubiquitination, and activation of GCKR and activation of the SAPK pathway in a manner that depends upon TRAF2 polyubiquitination and oligomerization and Ubc13 function PMID: 12591926
3. The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai. PMID: 16699725
亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
組織特異性：

Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
數(shù)據(jù)庫鏈接：

HGNC: 6867

OMIM: 604923

KEGG: hsa:11183

STRING: 9606.ENSP00000013125

UniGene: Hs.130491