Recombinant Mouse E3 ubiquitin-protein ligase RNF19B (Rnf19b), partial

中文名稱：

小鼠Rnf19b重組蛋白
貨號：

CSB-YP019867MO1
說明書：

Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Rnf19b重組蛋白
貨號：

CSB-EP019867MO1
說明書：

Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Rnf19b重組蛋白
貨號：

CSB-EP019867MO1-B
說明書：

Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rnf19b重組蛋白
貨號：

CSB-BP019867MO1
說明書：

Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rnf19b重組蛋白
貨號：

CSB-MP019867MO1
說明書：

Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rnf19b
Uniprot No.：

A2A7Q9
別名：

Rnf19b; Ibrdc3; Nklam; E3 ubiquitin-protein ligase RNF19B; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death.
基因功能參考文獻(xiàn)：
1. E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression. PMID: 25182373
2. Data show that Natural Killer Lytic-Associated Molecule (NKLAM) is a component of macrophage phagosomes and is involved in macrophage bactericidal functions. PMID: 23085241
3. support the role for NKLAM in NK function both in vitro and in vivo. PMID: 19915045
亞細(xì)胞定位：

Cytoplasmic granule membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

RBR family, RNF19 subfamily
組織特異性：

Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in macrophages (at protein level). Ubiquitously expressed with high expression in testis.
數(shù)據(jù)庫鏈接：

STRING: 10090.ENSMUSP00000131373

UniGene: Mm.259672