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Your Good Partner in Biology Research

ADRB2

ADRB2,全稱為β2腎上腺素能受體,是一種在多種組織細(xì)胞中廣泛表達(dá)的G蛋白偶聯(lián)受體。它參與調(diào)節(jié)多種生理功能,包括心血管系統(tǒng)、呼吸系統(tǒng)和代謝過(guò)程。ADRB2受體激動(dòng)劑是治療哮喘和慢性阻塞性肺病(COPD)等呼吸系統(tǒng)疾病的重要藥物,根據(jù)其作用持續(xù)時(shí)間,它們被分為短效、長(zhǎng)效和超長(zhǎng)效β-激動(dòng)劑。ADRB2在氣道平滑肌張力的重要調(diào)節(jié)劑,其功能異常與多種疾病的發(fā)生發(fā)展有關(guān),包括夜間哮喘、肥胖、2型糖尿病和心血管疾病。近年來(lái),ADRB2抑制劑在腫瘤預(yù)防和治療研究領(lǐng)域受到越來(lái)越多的關(guān)注,例如與索拉菲尼聯(lián)用治療肝癌。目前,針對(duì)ADRB2的藥物研發(fā)主要集中在開(kāi)發(fā)新型激動(dòng)劑和抑制劑,以治療呼吸系統(tǒng)疾病和腫瘤等疾病。

熱銷(xiāo)產(chǎn)品

Recombinant Human Beta-2 adrenergic receptor (ADRB2), partial (CSB-EP001392HU1)

驗(yàn)證數(shù)據(jù)

CSB-EP001392HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ADRB2 Recombinant Monoclonal Antibody (CSB-RA286054A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA286054A0HU

IHC image of CSB-RA286054A0HU diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA286054A0HU

IHC image of CSB-RA286054A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

ADRB2 Antibodies

ADRB2 for Homo sapiens (Human)

ADRB2 for Rattus norvegicus (Rat)

ADRB2 Proteins

ADRB2 Proteins for Rattus norvegicus (Rat)

ADRB2 Proteins for Mus musculus (Mouse)

ADRB2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

ADRB2 Proteins for Mesocricetus auratus (Golden hamster)

ADRB2 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)

ADRB2 Proteins for Sus scrofa (Pig)

ADRB2 Proteins for Macaca mulatta (Rhesus macaque)

ADRB2 Proteins for Bos taurus (Bovine)

ADRB2 Proteins for Tscherskia triton (Greater long-tailed hamster)

ADRB2 Proteins for Cavia porcellus (Guinea pig)

ADRB2 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

ADRB2 Proteins for Felis catus (Cat) (Felis silvestris catus)

ADRB2 Proteins for Homo sapiens (Human)