HAVCR2
HAVCR2，即甲型肝炎病毒細(xì)胞受體2，別名TIM-3（T細(xì)胞免疫球蛋白域和粘蛋白域-3）。它是一種主要在T細(xì)胞上表達(dá)的跨膜蛋白，屬于TIM家族成員之一。HAVCR2的作用機(jī)制涉及到與多種配體的結(jié)合，包括磷酸酶CD244和磷脂酰絲氨酸（PS），在免疫應(yīng)答中發(fā)揮調(diào)節(jié)作用，特別是作為抑制性受體參與調(diào)節(jié)T細(xì)胞的活性。HAVCR2在自身免疫性疾病、感染性疾病、腫瘤免疫監(jiān)視和免疫逃逸等免疫反應(yīng)的調(diào)節(jié)中發(fā)揮著不同的作用，是適應(yīng)性免疫中的一種抑制分子，且在某些腫瘤中表達(dá)水平的變化與疾病進(jìn)展相關(guān)，因此它也是免疫治療研究中的潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (CSB-EP010145HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HAVCR2 Recombinant Monoclonal Antibody (CSB-RA010145MA1HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescence staining of Hela cell with CSB-RA010145MA1HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).
Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit (CSB-EL010145HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL010145HU
規(guī)格：96T/48T
靈敏度：11.75 pg/mL
檢測(cè)范圍：47 pg/mL-3000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
HAVCR2 Antibodies
HAVCR2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA010145GA01HU | HAVCR2 Antibody | Human | ELISA,WB |
| CSB-PA010145LC01HU | HAVCR2 Antibody, FITC conjugated | Human | |
| CSB-PA010145LA01HU | HAVCR2 Antibody | Human | ELISA, IF |
| CSB-PA010145LD01HU | HAVCR2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA010145LB01HU | HAVCR2 Antibody, HRP conjugated | Human | ELISA |
| CSB-RA010145MA1HU | HAVCR2 Recombinant Monoclonal Antibody | Human | ELISA, IF |
HAVCR2 Proteins
HAVCR2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010145RA CSB-EP010145RA CSB-BP010145RA CSB-MP010145RA CSB-EP010145RA-B |
Recombinant Rat Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HAVCR2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP010145HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | Yeast |
| CSB-EP010145HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | E.coli |
| CSB-BP010145HU CSB-EP010145HU-B |
Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP010145HU1 | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | Mammalian cell |
| CSB-AP005281HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active) | Mammalian cell |
| CSB-AP005291HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active) | Mammalian cell |
HAVCR2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP840881MO CSB-EP840881MO CSB-BP840881MO CSB-MP840881MO CSB-EP840881MO-B |
Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP005341MO | Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial (Active) | Mammalian cell |
HAVCR2 ELISA Kit
HAVCR2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL010145HU | Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit | serum, plasma, tissue homogenates | 11.75 pg/mL |
