PAX6
PAX6，即配對(duì)框基因6，是一種在進(jìn)化上高度保守的轉(zhuǎn)錄因子，由PAX6基因編碼。它在眼睛、大腦、鼻子和胰腺等器官的發(fā)育中起著至關(guān)重要的作用。PAX6通過(guò)結(jié)合特定的DNA序列，調(diào)控下游基因的表達(dá)，從而參與多種生物學(xué)過(guò)程，包括胚胎發(fā)育和器官形成。PAX6的功能異常與多種眼部疾病相關(guān)，如先天性白內(nèi)障、無(wú)虹膜和小眼球癥等。此外，PAX6還涉及到腫瘤發(fā)生等過(guò)程，其在腫瘤中的表達(dá)變化可能影響腫瘤細(xì)胞的增殖和分化。PAX6參與的信號(hào)通路包括但不限于MEK/ERK信號(hào)通路，該通路在肝星狀細(xì)胞的活化和增殖中發(fā)揮作用。總的來(lái)說(shuō)，PAX6是一個(gè)多功能的調(diào)控分子，對(duì)維持生物體的正常發(fā)育和生理功能至關(guān)重要。
熱銷產(chǎn)品
Recombinant Human Paired box protein Pax-6 (PAX6) (CSB-EP017492HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PAX6 Recombinant Monoclonal Antibody (CSB-RA577229A0HU)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-RA577229A0HU diluted at 1:100 and staining in paraffin-embedded human pancreati tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.55% DAB.
IHC image of CSB-RA577229A0HU diluted at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.55% DAB.
Overlay Peak curve showing SH-SY5Y cells stained with CSB-RA577229A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
Mouse paired box 6 (PAX6) ELISA kit (CSB-EL017492MO)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL017492MO
規(guī)格：96T/48T
靈敏度：11.72 pg/mL
檢測(cè)范圍：46.88 pg/mL-3000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PAX6 Antibodies
PAX6 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017492GA01HU | PAX6 Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA017492DSR1HU | PAX6 Antibody | Human | ELISA, IHC |
| CSB-PA017492DSR2HU | PAX6 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-RA577229A0HU | PAX6 Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
PAX6 Proteins
PAX6 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492HU CSB-BP017492HU CSB-MP017492HU CSB-EP017492HU-B |
Recombinant Human Paired box protein Pax-6 (PAX6) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017492HU | Recombinant Human Paired box protein Pax-6 (PAX6) | E.coli |
PAX6 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492CH CSB-EP017492CH CSB-BP017492CH CSB-MP017492CH CSB-EP017492CH-B |
Recombinant Chicken Paired box protein Pax-6 (PAX6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492MO CSB-EP017492MO CSB-BP017492MO CSB-MP017492MO CSB-EP017492MO-B |
Recombinant Mouse Paired box protein Pax-6 (Pax6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492RA CSB-EP017492RA CSB-BP017492RA CSB-MP017492RA CSB-EP017492RA-B |
Recombinant Rat Paired box protein Pax-6 (Pax6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492DXJ CSB-EP017492DXJ CSB-BP017492DXJ CSB-MP017492DXJ CSB-EP017492DXJ-B |
Recombinant Coturnix coturnix japonica Paired box protein Pax-6 (PAX6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492XBE CSB-EP017492XBE CSB-BP017492XBE CSB-MP017492XBE CSB-EP017492XBE-B |
Recombinant Xenopus laevis Paired box protein Pax-6 (pax6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017492OFH CSB-EP017492OFH CSB-BP017492OFH CSB-MP017492OFH CSB-EP017492OFH-B |
Recombinant Oryzias latipes Paired box protein Pax-6 (pax6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP635859BO CSB-EP635859BO CSB-BP635859BO CSB-MP635859BO CSB-EP635859BO-B |
Recombinant Bovine Paired box protein Pax-6 (PAX6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAX6 ELISA Kit
PAX6 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL017492MO | Mouse paired box 6 (PAX6) ELISA kit | serum, plasma, tissue homogenates | 11.72 pg/mL |
