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PGF

PGF,即胎盤生長因子,是VEGF家族成員之一,別名PlGF-2等。它源自胎盤滋養(yǎng)層細(xì)胞,是妊娠期重要的血管生成因子。PGF通過結(jié)合VEGF受體,促進(jìn)血管內(nèi)皮細(xì)胞增殖、遷移,增強(qiáng)血管通透性與穩(wěn)定性,對(duì)胚胎滋養(yǎng)層生長、胎盤血管形成及母胎循環(huán)建立至關(guān)重要。此外,PGF水平變化可反映胎盤功能及妊娠狀態(tài),是監(jiān)測(cè)妊娠期高血壓、子癇前期等妊娠并發(fā)癥的生物標(biāo)志物。PGF也參與多種病理過程,如心血管疾病、腫瘤生長等,具有廣泛的生物學(xué)意義和研究價(jià)值。近年來,針對(duì)PGF及其受體的藥物研發(fā)取得顯著進(jìn)展,例如抗VEGF藥物恩格列凈等,為相關(guān)疾病的治療提供了新思路。

熱銷產(chǎn)品

Recombinant Human Placenta growth factor (PGF) (Active) (CSB-MP017854HU)

驗(yàn)證數(shù)據(jù)

CSB-MP017854HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP017854HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human FLT1(CSB-MP008732HU) protein at 2 μg/ml can bind Human PGF protein. The EC50 is 10.72-15.25 ng/mL.

Recombinant Human Placenta growth factor (PGF) (CSB-MP017854HU(F1))

驗(yàn)證數(shù)據(jù)

CSB-MP017854HU(F1)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP017854HU(F1)

The purity of PGF was greater than 95% as determined by SEC-HPLC

PGF Recombinant Monoclonal Antibody (CSB-RA280380A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA280380A0HU

IHC image of CSB-RA280380A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA280380A0HU

IHC image of CSB-RA280380A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human placenta growth factor,PLGF ELISA kit (CSB-E04707h)

驗(yàn)證數(shù)據(jù)

CSB-E04707h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E04707h

規(guī)格:96T/48T

靈敏度:0.7 ng/mL

檢測(cè)范圍:1.67 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PGF Antibodies

PGF for Homo sapiens (Human)

PGF Proteins

PGF Proteins for Homo sapiens (Human)

PGF Proteins for Mus musculus (Mouse)

PGF Proteins for Rattus norvegicus (Rat)

PGF Proteins for Bos taurus (Bovine)

PGF ELISA Kit

PGF ELISA Kit for Homo sapiens (Human)

PGF ELISA Kit for Rattus norvegicus (Rat)