TNFSF13B
TNFSF13B，即腫瘤壞死因子超家族成員13B，別名BLyS、BAFF、TALL-1。它是一種主要由B細(xì)胞產(chǎn)生的細(xì)胞因子，屬于腫瘤壞死因子超家族成員，在B細(xì)胞的成熟和存活中發(fā)揮關(guān)鍵作用。TNFSF13B的作用機(jī)制涉及與其受體BAFF-R結(jié)合，激活下游的信號(hào)傳導(dǎo)途徑，如NF-κB和JAK/STAT通路，促進(jìn)B細(xì)胞的增殖和分化。TNFSF13B在生物學(xué)上的意義非常廣泛，它參與了B細(xì)胞的發(fā)育、自身免疫性疾病的發(fā)生以及腫瘤的生長(zhǎng)。TNFSF13B的異常表達(dá)與某些B細(xì)胞相關(guān)疾病，如系統(tǒng)性紅斑狼瘡、類風(fēng)濕關(guān)節(jié)炎和某些類型的非霍奇金淋巴瘤有關(guān)，使其成為治療這些疾病的潛在靶點(diǎn)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFSF13B Antibody (CSB-PA981923)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: K562 cells, 231 cells, SKOV3 cells, Primary antibody: CSB-PA981923(TNFSF13B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
TNFSF13B Antibodies
TNFSF13B for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023990GA01HU | TNFSF13B Antibody | Human | ELISA,WB |
| CSB-PA05767A0Rb | TNFSF13B Antibody | Human | ELISA |
| CSB-PA897523ESR2HU | TNFSF13B Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA005018 | TNFSF13B Antibody | Human,Mouse | WB, ELISA |
| CSB-PA981923 | TNFSF13B Antibody | Human | ELISA,WB,IHC |
| CSB-PA108957 | TNFSF13B Antibody | Human | ELISA,IHC |
TNFSF13B Proteins
TNFSF13B Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP894359MO CSB-EP894359MO CSB-BP894359MO CSB-MP894359MO CSB-EP894359MO-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 13B (Tnfsf13b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF13B Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP897523HU CSB-BP897523HU CSB-MP897523HU CSB-EP897523HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP897523HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B), partial | E.coli |
| CSB-AP002191HU | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | E.Coli |
| CSB-MP897523HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active) | Mammalian cell |
| CSB-MP897523HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial,Biotinylated (Active) | Mammalian cell |
TNFSF13B ELISA Kit
TNFSF13B ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11912h | Human B cell activation factor，BAFF ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
